Алексей Сергушичев
Исследовательские группы
Биография
Алексей окончил в 2013 году Санкт-Петербургский национальный исследовательский университет информационных технологий, механики и оптики (ИТМО) и получил степень магистра с отличием в области компьютерных наук. В родном университете защитил кандидатскую под руководством Максима Артемова. Его работа посвящена разработке методов для вычислительных задач биологии, в частности для анализа метаболических сетей.
Ссылки
Публикации
LKB1 expressed in dendritic cells governs the development and expansion of thymus-derived regulatory T cells
April 2019
Leonard R. Pelgrom, Thiago A. Patente, Alexey Sergushichev, Ekaterina Esaulova, Frank Otto, Arifa Ozir-Fazalalikhan, Hendrik J. P. van der Zande, Alwin J. van der Ham, Stefan van der Stel, Maxim N. Artyomov & Bart Everts
Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis
April 2018
Monika Bambouskova, Laurent Gorvel, Vicky Lampropoulou, Alexey Sergushichev, Ekaterina Loginicheva, Kendall Johnson, Daniel Korenfeld, Mary Elizabeth Mathyer, Hyeryun Kim, Li-Hao Huang, Dustin Duncan, Howard Bregman, Abdurrahman Keskin, Andrea Santeford, Rajendra S. Apte, Raghav Sehgal, Britney Johnson, Gaya K. Amarasinghe, Miguel P. Soares, Takashi Satoh, Shizuo Akira, Tsonwin Hai, Cristina de Guzman Strong, Karine Auclair, Thomas P. Roddy, Scott A. Biller, Marko Jovanovic, Eynav Klechevsky, Kelly M. Stewart, Gwendalyn J. Randolph & Maxim N. Artyomov
Draft Genome Sequence of Coxiella burnetii Historical Strain Leningrad-2, Isolated from Blood of a Patient with Acute Q Fever in Saint Petersburg, Russia
January 2018
Olga Freylikhman, Artem Kiselev, Sergey Kazakov, Alexey Sergushichev, Yulia Panferova, Nikolay Tokarevich, Anna Kostareva
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease
August 2017
Tyler K. Ulland, Wilbur M. Song, Stanley Ching-Cheng Huang, Jason D. Ulrich, Alexey Sergushichev, Wandy L. Beatty, Alexander A. Loboda, Yingyue Zhou, Nigel J. Cairns, Amal Kambal, Ekaterina Loginicheva, Susan Gilfillan, Marina Cella, Herbert W. Virgin, Emil R. Unanue, Yaming Wang, Maxim N. Artyomov, David M. Holtzman, Marco Colonna
Ranking Vertices for Active Module Recovery Problem
April 2017
Javlon E. Isomurodov, Alexander A. Loboda, Alexey A. Sergushichev
Integrating immunometabolism and macrophage diversity
October 2016
Maxim N. Artyomov, Alexey Sergushichev, Joel D. Schilling
Solving Generalized Maximum-Weight Connected Subgraph Problem for Network Enrichment Analysis
August 2016
Alexander A. Loboda, Maxim N. Artyomov, Alexey A. Sergushichev
Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
July 2016
V. Lampropoulou, A. Sergushichev, M. Bambouskova, S. Nair, E. Vincent, E. Loginicheva, L. Cervantes-Barragan, X. Ma, S. Huang, T. Griss, C. Weinheimer, S. Khader, G. Randolph, E. Pearce, R. G. Jones, A. Diwan, M. Diamond,M. N. Artyomov
GAM: a web-service for integrated transcriptional and metabolic network analysis
April 2016
Alexey A. Sergushichev, Alexander A. Loboda, Abhishek K. Jha, Emma E. Vincent, Edward M. Driggers, Russell G. Jones, Edward J. Pearce and Maxim N. Artyomov
Mitochondrial Phosphoenolpyruvate Carboxykinase Regulates Metabolic Adaptation and Enables Glucose-Independent Tumor Growth
October 2015
E. Vincent, A. Sergushichev, T. Griss, M. Gingras, B. Samborska, T. Ntimbane, P. Coelho, J. Blagih, T. Raissi, L. Choinière, G. Bridon, E. Loginicheva, B. Flynn, E. Thomas, J. Tavaré, D. Avizonis, A. Pause, D. Elder, M. Artyomov, R. Jones
Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
March 2015
Abhishek K. Jha, Stanley Ching-Cheng Huang, Alexey Sergushichev, Vicky Lampropoulou, Yulia Ivanova, Ekaterina Loginicheva, Karina Chmielewski, Kelly M. Stewart, Juliet Ashall, Bart Everts, Edward J. Pearce, Edward M. Driggers, and Maxim N. Artyomov