Константин Зайцев
Исследовательские группы
Биография
Окончил бакалавриат (2015) и магистратуру (2017) Университета ИТМО, факультет информационных технологий и программирования.
В 2015 году в рамках магистратуры присоединился к группе Максима Артёмова, чтобы решать задачу деконволюции данных экспрессии генов. Провёл больше года в Университете Вашингтона в Сент-Луисе на факультете иммунологии и патологии в качестве исследователя.
А данный момент аспирант в университете ИТМО.
Научные интересы - технологии секвенирования одиночных клеток, анализ данных экспрессии генов и иммунология.
Научный руководитель – Максим Артёмов.
Публикации
Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging
December 2020
Denis A. Mogilenko, Oleg Shpynov, Prabhakar Sairam Andhey, Laura Arthur, Amanda Swain, Ekaterina Esaulova, Simone Brioschi, Irina Shchukina, Martina Kerndl, Monika Bambouskova, Zhangting Yao, Anwesha Laha, Konstantin Zaitsev, Samantha Burdess, Susan Gillfilan, Sheila A. Stewart, Marco Colonna, Maxim N.Artyomov
Single-cell RNA-seq analysis of human CSF microglia and myeloid cells in neuroinflammation
July 2020
Ekaterina Esaulova, Claudia Cantoni, Irina Shchukina, Konstantin Zaitsev, Robert C Bucelli, Gregory F Wu, Maxim N Artyomov, Anne H Cross, Brian T Edelson
Single cell RNA sequencing in atherosclerosis research
April 2020
Jesse W Williams, Holger Winkels, Christopher P Durant, Konstantin Zaitsev, Yanal Ghosheh, Klaus Ley
Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes
February 2020
Ya-Ting Wang, Konstantin Zaitsev, Qun Lu, Shan Li, W Timothy Schaiff, Ki-Wook Kim, Lindsay Droit, Craig B Wilen, Chandni Desai, Dale R Balce, Robert C Orchard, Anthony Orvedahl, Sunmin Park, Darren Kreamalmeyer, Scott A Handley, John D Pfeifer, Megan T Baldridge, Maxim N Artyomov, Christina L Stallings, Herbert W Virgin
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease
January 2020
Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A Bennett, Julie A Schneider, Michael R Nichols, Sean A Beausoleil, Jason D Ulrich, David M Holtzman, Maxim N Artyomov, Marco Colonna
Subsets of ILC3− ILC1-like cells generate a diversity spectrum of innate lymphoid cells in human mucosal tissues
August 2019
Marina Cella, Ramya Gamini, Cristiane Sécca, Patrick L Collins, Shanrong Zhao, Vincent Peng, Michelle L Robinette, Jorge Schettini, Konstantin Zaitsev, William Gordon, Jennifer K Bando, Kentaro Yomogida, Victor Cortez, Catrina Fronick, Robert Fulton, Lih-Ling Lin, Susan Gilfillan, Richard A Flavell, Liang Shan, Maxim N Artyomov, Michael Bowman, Eugene M Oltz, Scott A Jelinsky, Marco Colonna
Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells
August 2019
Eugene Park, Swapneel Patel, Qiuling Wang, Prabhakar Andhey, Konstantin Zaitsev, Sophia Porter, Maxwell Hershey, Michael Bern, Beatrice Plougastel-Douglas, Patrick Collins, Marco Colonna, Kenneth M Murphy, Eugene Oltz, Maxim Artyomov, L David Sibley, Wayne M Yokoyama
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures
May 2019
Konstantin Zaitsev, Monika Bambouskova, Amanda Swain, Maxim N Artyomov
Tissue resident CCR2− and CCR2+ cardiac macrophages differentially orchestrate monocyte recruitment and fate specification following myocardial injury
January 2019
Geetika Bajpai, Andrea Bredemeyer, Wenjun Li, Konstantin Zaitsev, Andrew L Koenig, Inessa Lokshina, Jayaram Mohan, Brooke Ivey, His-Min Hsiao, Carla Weinheimer, Attila Kovacs, Slava Epelman, Maxim Artyomov, Daniel Kreisel, Kory J Lavine
Interferon lambda protects the female reproductive tract against Zika virus infection
January 2019
Elizabeth A Caine, Suzanne M Scheaffer, Nitin Arora, Konstantin Zaitsev, Maxim N Artyomov, Carolyn B Coyne, Kelle H Moley, Michael S Diamond
Transcriptome Analysis Reveals Nonfoamy Rather Than Foamy Plaque Macrophages Are Proinflammatory in Atherosclerotic Murine Models
October 2018
Kyeongdae Kim , Dahee Shim , Jun Seong Lee , Konstantin Zaitsev , Jesse W. Williams , Ki-Wook Kim , Man-Young Jang , Hyung Seok Jang , Tae Jin Yun , Seung Hyun Lee , Won Kee Yoon , Annik Prat , Nabil G. Seidah , Jungsoon Choi , Seung-Pyo Lee , Sang-Ho Yoon , Jin Wu Nam , Je Kyung Seong , Goo Taeg Oh , Gwendalyn J. Randolph , Maxim N. Artyomov , Cheolho Cheong , and Jae-Hoon Choi
An Immunocompetent Mouse Model of Zika Virus Infection
May 2018
Matthew J. Gorman, Elizabeth A. Caine, Konstantin Zaitsev, Matthew C. Begley, James Weger-Lucarelli, Melissa B. Uccellini, Shashank Tripathi, Juliet Morrison, Boyd L. Yount, Kenneth H. Dinnon III, Claudia Rückert, Michael C. Young, Zhe Zhu, Shelly J. Robertson, Kristin L. McNally, Jing Ye, Bin Cao, Indira U. Mysorekar, Gregory D. Ebel, Ralph S. Baric, Sonja M. Best, Maxim N. Artyomov, Adolfo Garcia-Sastre, Michael S. Diamond
Opposing Roles of Dendritic Cell Subsets in Experimental GN
January 2018
Sebastian Brähler, Bernd H. Zinselmeyer, Saravanan Raju, Maximilian Nitschke, Hani Suleiman, Brian T. Saunders, Michael W. Johnson, Alexander M.C. Böhner, Susanne F. Viehmann, Derek J. Theisen, Nicole M. Kretzer, Carlos G. Briseño, Konstantin Zaitsev, Olga Ornatsky, Qing Chang, Javier A. Carrero, Jeffrey B. Kopp, Maxim N. Artyomov, Christian Kurts, Kenneth M. Murphy, Jeffrey H. Miner and Andrey S. Shaw
POSTER: Systems Level Characterization of the Epigenomic Changes During Healthy Aging in the Human Blood Monocyte
October 2016
Bagaitkar Juhi, Bambouskova Monica, Oltz Eugene, Porter Sofia, Collins Patrick, Shpynov Oleg, German Demidov, Konstantin Zaytsev